Recombinant Human ITGA7 Protein, GST-tagged

• Cat.No.: ITGA7-4994H
• Product Overview: Human ITGA7 partial ORF ( NP_002197, 478 a.a. - 577 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. They mediate a wide spectrum of cell-cell and cell-matrix interactions, and thus play a role in cell migration, morphologic development, differentiation, and metastasis. This protein functions as a receptor for the basement membrane protein laminin-1. It is mainly expressed in skeletal and cardiac muscles and may be involved in differentiation and migration processes during myogenesis. Defects in this gene are associated with congenital myopathy. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.74 kDa
• AA Sequence: SHEVSIAPRSIDLEQPNCAGGHSVC VDLRVCFSYIAVPSSYSPTVALDYV LDADTDRRLRGQVPRVTFLSRNLEE PKHQASGTVWLKHQHDRVCGDAMFQ
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ITGA7 integrin, alpha 7 [ Homo sapiens ]
• Official Symbol: ITGA7
• Synonyms: ITGA7; integrin, alpha 7; integrin alpha-7; integrin alpha 7 chain; FLJ25220
• Gene ID: 3679
• mRNA Refseq: NM_001144996
• Protein Refseq: NP_001138468
• MIM: 600536
• UniProt ID: Q13683