Recombinant Human ITGB1 Protein, GST-tagged
Cat.No. : | ITGB1-4986H |
Product Overview : | Human ITGB1 full-length ORF ( AAH20057.1, 1 a.a. - 798 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
- Download
Description : | Integrins are heterodimeric proteins made up of alpha and beta subunits. At least 18 alpha and 8 beta subunits have been described in mammals. Integrin family members are membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. This gene encodes a beta subunit. Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene. [provided by RefSeq |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 114.8 kDa |
AA Sequence : | MNLQPIFWIGLISSVCCVFAQTDEN RCLKANAKSCGECIQAGPNCGWCTN STFLQEGMPTSARCDDLEALKKKGC PPDDIENPRGSKDIKKNKNVTNRSK GTAEKLKPEDITQIQPQQLVLRLRS GEPQTFTLKFKRAEDYPIDLYYLMD LSYSMKDDLENVKSLGTDLMNEMRR ITSDFRIGFGSFVEKTVMPYISTTP AKLRNPCTSEQNCTSPFSYKNVLSL TNKGEVFNELVGKQRISGNLDSPEG GFDAIMQVAVCGSLIGWRNVTRLLV FSTDAGFHFAGDGKLGGIVLPNDGQ CHLENNMYTMSHYYDYPSIAHLVQK LSENNIQTIFAVTEEFQPVYKELKN LIPKSAVGTLSANSSNVIQLIIDAY NSLSSEVILENGKLSEGVTISYKSY CKNGVNGTGENGRKCSNISIGDEVQ FEISITSNKCPKKDSDSFKIRPLGF TEEVEVILQYICECECQSEGIPESP KCHEGNGTFECGACRCNEGRVGRHC ECSTDEVNSEDMDAYCRKENSSEIC SNNGECVCGQCVCRKRDNTNEIYSG KFCECDNFNCDRSNGLICGGNGVCK CRVCECNPNYTGSACDCSLDTSTCE ASNGQICNGRGICECGVCKCTDPKF QGQTCEMCQTCLGVCAEHKECVQCR AFNKGEKKDTCTQECSYFNITKVES RDKLPQPVQPDPVSHCKEKDVDDCW FYFTYSVNGNNEVMVHVVENPECPT GPDIIPIVAGVVAGIVLIGLALLLI WKLLMIIHDRREFAKFEKEKMNAKW DTGENPIYKSAVTTVVNPKYEGK |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) [ Homo sapiens ] |
Official Symbol : | ITGB1 |
Synonyms : | ITGB1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); FNRB, MDF2, MSK12; integrin beta-1; CD29; GPIIA; integrin VLA-4 beta subunit; very late activation protein, beta polypeptide; FNRB; MDF2; VLAB; MSK12; VLA-BETA; |
Gene ID : | 3688 |
mRNA Refseq : | NM_002211 |
Protein Refseq : | NP_002202 |
MIM : | 135630 |
UniProt ID : | P05556 |
Products Types
◆ Recombinant Protein | ||
Itgb1-3603M | Recombinant Mouse Itgb1 Protein, Myc/DDK-tagged | +Inquiry |
ITGB1-590R | Recombinant Rat ITGB1 Protein (21-729 aa), His-SUMO-tagged | +Inquiry |
ITGB1-2770R | Recombinant Rat ITGB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ITGB1-4642M | Recombinant Mouse ITGB1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ITGB1-2484H | Recombinant human ITGB1, His-tagged | +Inquiry |
◆ Lysates | ||
ITGB1-5128HCL | Recombinant Human ITGB1 293 Cell Lysate | +Inquiry |
ITGB1-5127HCL | Recombinant Human ITGB1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionTherapeutic strategies for ITGB1 protein may include inhibiting its expression, blocking its binding to ligands, or regulating its associated signal transduction pathways. These methods may have potential applications in cancer treatment.
The ITGB1 protein can interact with a variety of other proteins, including ligands, proteins in signal transduction pathways, etc. These interactions enable it to regulate processes such as cell growth, differentiation, and apoptosis.
In cancer, ITGB1 protein may play a role by promoting processes such as the proliferation, migration and invasion of tumor cells, thus promoting the occurrence and development of tumors. It could be a potential target for cancer treatment.
The main function of ITGB1 protein in cells is to act as a cell adhesion receptor, participate in the interaction between cells and extracellular matrix, and play an important role in cell migration and signal transduction.
The structure of the ITGB1 protein determines its ability and stability to bind to ligands. The study of its structure can help us understand its function and mechanism of action.
Recent literature has shown that the expression level of ITGB1 protein is related to the occurrence and development of a variety of diseases, including cancer, cardiovascular diseases, neurodegenerative diseases, etc.
Customer Reviews (3)
Write a reviewThe range of applications for ITGB1 is impressive, and it can play an important role in any field.
ITGB1 performed very well in Western blot, with clear bands and improved experimental accuracy.
ITGB1 has a strong desensitization potential for specific allergens.
Ask a Question for All ITGB1 Products
Required fields are marked with *
My Review for All ITGB1 Products
Required fields are marked with *
Inquiry Basket