Recombinant Human ITGB3 protein, MYC/DDK-tagged ITGB3-12H

Recombinant Human ITGB3 protein, MYC/DDK-tagged

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Recombinant Human ITGB3 protein, MYC/DDK-tagged

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Cat.No. : ITGB3-12H
Product Overview : Recombinant Human ITGB3 fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description : The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 84.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) [ Homo sapiens ]
Official Symbol : ITGB3
Synonyms : ITGB3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); GP3A; integrin beta-3; CD61; GPIIIa; platelet glycoprotein IIIa; platelet membrane glycoprotein IIIa; GT; BDPLT2;
Gene ID : 3690
mRNA Refseq : NM_000212
Protein Refseq : NP_000203
MIM : 173470
UniProt ID : P05106
Chromosome Location : 17q21.32
Pathway : Arf6 signaling events, organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), organism-specific biosystem; Arrhythmogenic right ventricular cardiomyopathy (ARVC), conserved biosystem; Axon guidance, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Dilated cardiomyopathy, organism-specific biosystem;
Function : cell adhesion molecule binding; identical protein binding; integrin binding; platelet-derived growth factor receptor binding; protein binding; protein disulfide isomerase activity; receptor activity; vascular endothelial growth factor receptor 2 binding; vascular endothelial growth factor receptor 2 binding;

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