Recombinant Human ITPR3 Protein, His&GST-tagged

• Cat.No.: ITPR3-1701H
• Product Overview: Recombinant Human ITPR3 Protein (Phe2389-Asp2496) with N-His&GST tag was expressed in E. coli.

Specification

• Description: This gene encodes a receptor for inositol 1,4,5-trisphosphate, a second messenger that mediates the release of intracellular calcium. The receptor contains a calcium channel at the C-terminus and the ligand-binding site at the N-terminus. Knockout studies in mice suggest that type 2 and type 3 inositol 1,4,5-trisphosphate receptors play a key role in exocrine secretion underlying energy metabolism and growth.
• Source: E. coli
• Species: Human
• Tag: N-His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 41.8 kDa
  Accurate Molecular Mass: 42 kDa
• Protein length: Phe2389-Asp2496
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 [ Homo sapiens (human) ]
• Official Symbol: ITPR3
• Synonyms: ITPR3; inositol 1,4,5-trisphosphate receptor, type 3; inositol 1,4,5 triphosphate receptor, type 3; inositol 1,4,5-trisphosphate receptor type 3; IP3R3; insP3R3; IP3 receptor; type 3 InsP3 receptor; inositol 1,4,5-triphosphate receptor, type 3; IP3R; FLJ36205
• Gene ID: 3710
• mRNA Refseq: NM_002224
• Protein Refseq: NP_002215
• MIM: 147267
• UniProt ID: Q14573