JAK3-006H
Optional Service: Optional requirements on this protein
Product Overview :
JAK3 MS Standard C13 and N15-labeled recombinant protein (NP_000206) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :
The protein encoded by this gene is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).
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