Recombinant Human JPT1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | JPT1-1845H |
Product Overview : | HN1 MS Standard C13 and N15-labeled recombinant protein (NP_001002033) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | Modulates negatively AKT-mediated GSK3B signaling. Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions. Plays a role in the regulation of cell cycle and cell adhesion. Has an inhibitory role on AR-signaling pathway through the induction of receptor proteosomal degradation. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 11 kDa |
AA Sequence : | MASNIFGTPEENQASWAKSAGAKSS GGREDLESSGLQRRNSSEASSGDFL DLKGEGDIHENVDTDLPGSLGQSEE KPVPAAPVPSPVAPAPVPSRRNPPG GKSSLVLGTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | JPT1 Jupiter microtubule associated homolog 1 [ Homo sapiens (human) ] |
Official Symbol : | JPT1 |
Synonyms : | JPT1; Jupiter microtubule associated homolog 1; HN1; ARM2; HN1A; jupiter microtubule associated homolog 1; androgen-regulated protein 2; hematological and neurological expressed 1 protein |
Gene ID : | 51155 |
mRNA Refseq : | NM_001002033 |
Protein Refseq : | NP_001002033 |
UniProt ID : | Q9UK76 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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