Recombinant Human KCTD6 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | KCTD6-870H |
Product Overview : | KCTD6 MS Standard C13 and N15-labeled recombinant protein (NP_699162) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Involved in regulating protein levels of ANK1 isoform Mu17 probably implicating CUL3-dependent proteasomal degradation. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 27.6 kDa |
AA Sequence : | MDNGDWGYMMTDPVTLNVGGHLYTT SLTTLTRYPDSMLGAMFGGDFPTAR DPQGNYFIDRDGPLFRYVLNFLRTS ELTLPLDFKEFDLLRKEADFYQIEP LIQCLNDPKPLYPMDTFEEVVELSS TRKLSKYSNPVAVIITQLTITTKVH SLLEGISNYFTKWNKHMMDTRDCQV SFTFGPCDYHQEVSLRVHLMEYITK QGFTIRNTRVHHMSERANENTVEHN WTFCRLARKTDDSGPTRTRPLEQKL ISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | KCTD6 potassium channel tetramerisation domain containing 6 [ Homo sapiens (human) ] |
Official Symbol : | KCTD6 |
Synonyms : | KCTD6; potassium channel tetramerisation domain containing 6; BTB/POZ domain-containing protein KCTD6; KCASH3; MGC27385; |
Gene ID : | 200845 |
mRNA Refseq : | NM_153331 |
Protein Refseq : | NP_699162 |
MIM : | 618791 |
UniProt ID : | Q8NC69 |
Products Types
◆ Recombinant Protein | ||
Kctd6-3675M | Recombinant Mouse Kctd6 Protein, Myc/DDK-tagged | +Inquiry |
KCTD6-2726H | Recombinant Human KCTD6 Protein (Full Length), N-His tagged | +Inquiry |
KCTD6-1234H | Recombinant Human KCTD6 protein, GST-tagged | +Inquiry |
KCTD6-2660H | Recombinant Human KCTD6 protein, His-tagged | +Inquiry |
◆ Lysates | ||
KCTD6-894HCL | Recombinant Human KCTD6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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