Recombinant Mouse Kctd6 Protein, Myc/DDK-tagged
Cat.No. : | Kctd6-3675M |
Product Overview : | Purified recombinant protein of mouse full-length potassium channel tetramerisation domain containing 6 (Kctd6), with C-terminal MYC/DDK tag, expressed in HEK293T cells. |
- Specification
- Gene Information
- Related Products
Description : | Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1; the function seems to depend on KCTD11:KCTD6 oligomerization. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB). Involved in regulating protein levels of ANK1 isoform Mu7 probably implicating CUL3-dependent proteasomal degradation. |
Source : | HEK293T |
Species : | Mouse |
Tag : | Myc/DDK |
Molecular Mass : | 27.6 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade after receiving vials. |
Concentration : | >50 μg/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | Kctd6 potassium channel tetramerisation domain containing 6 [ Mus musculus (house mouse) ] |
Official Symbol : | Kctd6 |
Synonyms : | KCTD6; potassium channel tetramerisation domain containing 6; BTB/POZ domain-containing protein KCTD6; AU044285; 5430433B02Rik |
Gene ID : | 71393 |
mRNA Refseq : | NM_027782 |
Protein Refseq : | NP_082058 |
UniProt ID : | Q8BNL5 |
Products Types
◆ Recombinant Protein | ||
KCTD6-1234H | Recombinant Human KCTD6 protein, GST-tagged | +Inquiry |
KCTD6-2726H | Recombinant Human KCTD6 Protein (Full Length), N-His tagged | +Inquiry |
KCTD6-2660H | Recombinant Human KCTD6 protein, His-tagged | +Inquiry |
◆ Lysates | ||
KCTD6-894HCL | Recombinant Human KCTD6 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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