|Product Overview:||Recombinant Human KHK(Met1-Val298) fused with His tag at C-terminal was expressed in HEK293.|
|Description:||Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.This enzyme catalyzes conversion of fructose to fructose-1-phosphate. It is the first enzyme with a specialized pathway that catabolizes dietary fructose. Defects in KHK are the cause of fructosuria.|
|Form:||Supplied as a 0.2 μm filtered solution of 20mM TrisHCl,50nM KCl,10%Glycerol,pH7.4.|
|AA Sequence:||MEEKQILCVGLVVLDVISLVDKYPKEDSEIRCLSQRWQRGGNASNSCTILSLLGAPCAFMGSMAP GHVADFVLDDLRRYSVDLRYTVFQTTGSVPIATVIINEASGSRTILYYDRSLPDVSATDFEKVDL TQFKWIHIEGRNASEQVKMLQRIDAHNTRQPPEQKIRVSVEVEKPREELFQLFGYGDVVFVSKDV AKHLGFQSAEEALRGLYGRVRKGAVLVCAWAEEGADALGPDGKLLHSDAFPPPRVVDTLGAGDTF NASVIFSLSQGRSVQEALRFGCQVAGKKCGLQGFDGIVVDHHHHHH|
|Endotoxin:||Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.|
|Purity:||Greater than 95% as determined by reducing SDS-PAGE.|
|Storage:||Store at < -20 centigrade, stable for 6 months after receipt.
Please minimize freeze-thaw cycles.
|Shipping:||The product is shipped on dry ice/ice packs.|
|Gene Name:||KHK ketohexokinase (fructokinase) [ Homo sapiens ]|
|Synonyms:||KHK; ketohexokinase (fructokinase); ketohexokinase; hepatic fructokinase;|
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