Recombinant Human MTHFD2 protein, his-tagged
Cat.No. : | MTHFD2-22H |
Product Overview : | Recombinant Human MTHFD2 Protein was expressed in E.coli with His-tag. |
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Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid |
Molecular Mass : | 37.2 kDa |
AA Sequence : | MGSSHHHHHHSSGLVPRGSHMGSLA AVRNEAVVISGRKLAQQIKQEVRQE VEEWVASGNKRPHLSVILVGENPAS HSYVLNKTRAAAVVGINSETIMKPA SISEEELLNLINKLNNDDNVDGLLV QLPLPEHIDERRICNAVSPDKDVDG FHVINVGRMCLDQYSMLPATPWGVW EIIKRTGIPTLGKNVVVAGRSKNVG MPIAMLLHTDGAHERPGGDATVTIS HRYTPKEQLKKHTILADIVISAAGI PNLITADMIKEGAAVIDVGINRVHD PVTAKPKLVGDVDFEGVRQKAGYIT PVPGGVGPMTVAMLMKNTIIAAKKV LRLEEREVLKSKELGVATN |
Purity : | > 95 % by SDS-PAGE |
Storage : | Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20centigrade or -70centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/mL (determined by Bradford assay) |
Storage Buffer : | In Phosphate buffered saline (pH7.4) containing 20% glycerol, 1mM DTT |
Gene Name : | MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [ Homo sapiens (human) ] |
Official Symbol : | MTHFD2 |
Synonyms : | MTHFD2; methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase; NMDMC; bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial NAD-dependent methylene tetrahydrofolate dehydrogenase cyclohydrolase; EC 1.5.1.15; EC 3.5.4.9 |
Gene ID : | 10797 |
mRNA Refseq : | NM_006636 |
Protein Refseq : | NP_006627 |
MIM : | 604887 |
UniProt ID : | P13995 |
Products Types
◆ Recombinant Protein | ||
MTHFD2-1868B | Recombinant Bovine MTHFD2 Protein (36-350 aa), His-SUMO-tagged | +Inquiry |
Mthfd2-4210M | Recombinant Mouse Mthfd2 Protein, Myc/DDK-tagged | +Inquiry |
MTHFD2-5779M | Recombinant Mouse MTHFD2 Protein, His (Fc)-Avi-tagged | +Inquiry |
MTHFD2-136H | Recombinant Human MTHFD2 protein, T7-tagged | +Inquiry |
MTHFD2-395H | Recombinant Human MTHFD2, GST-tagged | +Inquiry |
◆ Lysates | ||
MTHFD2-4083HCL | Recombinant Human MTHFD2 293 Cell Lysate | +Inquiry |
MTHFD2-4082HCL | Recombinant Human MTHFD2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMTHFD2 is involved in the mitochondrial folate pathway, influencing the synthesis of nucleotides and methionine.
Some clinical trials are exploring the efficacy of MTHFD2 inhibitors in cancer treatment.
MTHFD2 expression is often dysregulated in cancer and other metabolic disorders.
Research is ongoing to develop inhibitors that selectively target MTHFD2, showing promise for cancer treatment.
Elevated MTHFD2 levels have been observed in certain cancers, suggesting its potential as a diagnostic marker.
Customer Reviews (3)
Write a reviewIt can also be employed in various molecular biology techniques, such as Western blotting, immunoprecipitation, or protein-protein interaction studies.
Its versatility allows researchers to explore MTHFD2's involvement in diverse biological processes and fully uncover its functional role.
the MTHFD2 protein's high quality, dependable performance, and comprehensive technical support make it an excellent choice for researchers seeking to investigate angiopoietin-related biology and unravel the complexities of vascular development and pathogenesis.
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