"KLF5" Related Products

Recombinant Human KLF5 protein, His-tagged

Cat.No.: KLF5-134H
Product Overview: Recombinant Human KLF5(Asp216~Asn457) fused with His tag at N-terminal was expressed in E. coli.
Description: This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. The encoded protein is a transcriptional activator that binds directly to a specific recognition motif in the promoters of target genes. This protein acts downstream of multiple different signaling pathways and is regulated by post-translational modification. It may participate in both promoting and suppressing cell proliferation. expression of this gene may be changed in a variety of different cancers and in cardiovascular disease. Alternative splicing results in multiple transcript variants.
Source: E. coli
Species: Human
Tag: His
Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300
Molecular Mass: 30.9kDa
Protein length: Asp216~Asn457
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 95%
Applications: SDS-PAGE; WB; ELISA; IP
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others.
Gene Name: KLF5 Kruppel-like factor 5 (intestinal) [ Homo sapiens ]
Official Symbol: KLF5
Synonyms: KLF5; Kruppel-like factor 5 (intestinal); BTEB2; Krueppel-like factor 5; CKLF; IKLF; BTE-binding protein 2; GC box binding protein 2; GC-box-binding protein 2; colon kruppel-like factor; colon krueppel-like factor; transcription factor BTEB2; intestinal-enriched kruppel-like factor; intestinal-enriched krueppel-like factor; basic transcription element binding protein 2; basic transcription element-binding protein 2;
Gene ID: 688
mRNA Refseq: NM_001730
Protein Refseq: NP_001721
MIM: 602903
UniProt ID: Q13887
Chromosome Location: 13q21.3
Pathway: Adipogenesis, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Transcriptional Regulation of White Adipocyte Differentiation, organism-specific biosystem;
Function: DNA binding; metal ion binding; sequence-specific DNA binding transcription factor activity; zinc ion binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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