Recombinant Human KPNA5 Protein, GST-tagged

• Cat.No.: KPNA5-4893H
• Product Overview: Human KPNA5 full-length ORF ( AAH47409.1, 1 a.a. - 539 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The transport of molecules between the nucleus and the cytoplasm in eukaryotic cells is mediated by the nuclear pore complex (NPC) which consists of 60-100 proteins and is probably 120 million daltons in molecular size. Small molecules (up to 70 kD) can pass through the nuclear pore by nonselective diffusion; larger molecules are transported by an active process. Most nuclear proteins contain short basic amino acid sequences known as nuclear localization signals (NLSs). KPNA5 protein belongs to the importin alpha protein family and is thought to be involved in NLS-dependent protein import into the nucleus. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 85.03 kDa
• AA Sequence: MDAMASPGKDNYRMKSYKNKALNPQ EMRRRREEEGIQLRKQKREEQLFKR RNVYLPRNDESMLESPIQDPDISST VPIPEEEVVTTDMVQMIFSNNADQQ LTATQKFRKLLSKEPNPPIDQVIQK PGVVQRFVKFLERNENCTLQFEAAW ALTNIASGTFLHTKVVIETGAVPIF IKLLNSEHEDVQEQAVWALGNIAGD NAECRDFVLNCEILPPLLELLTNSN RLTTTRNAVWALSNLCRGKNPPPNF SKVSPCLNVLSRLLFSSDPDVLADV CWALSYLSDGPNDKIQAVIDSGVCR RLVELLMHNDYKVVSPALRAVGNIV TGDDIQTQVILNCSALPCLLHLLSS PKESIRKEACWTVSNITAGNRAQIQ AVIDANIFPVLIEILQKAEFRTRKE AAWAITNATSGGTPEQIRYLVALGC IKPLCDLLTVMDSKIVQVALNGLEN ILRLGEQESKQNGIGINPYCALIEE AYGLDKIEFLQSHENQEIYQKAFDL IEHYFGVEEDDPSIVPQVDENQQQF IFQQQEAPMDGFQL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: KPNA5 karyopherin alpha 5 (importin alpha 6) [ Homo sapiens ]
• Official Symbol: KPNA5
• Synonyms: KPNA5; karyopherin alpha 5 (importin alpha 6); importin subunit alpha-6; IPOA6; SRP6; importin alpha 6; karyopherin subunit alpha-5
• Gene ID: 3841
• mRNA Refseq: NM_002269
• Protein Refseq: NP_002260
• MIM: 604545
• UniProt ID: O15131