Recombinant Human KRT16, GST-tagged

• Cat.No.: KRT16-455H
• Product Overview: Recombinant Human KRT16 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 121-473aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: KRT16 keratin 16 [ Homo sapiens ]
• Official Symbol: KRT16
• Synonyms: KRT16; keratin 16; keratin, type I cytoskeletal 16; CK-16; keratin-16; cytokeratin 16; cytokeratin-16; focal non-epidermolytic palmoplantar keratoderma; K16; CK16; K1CP; NEPPK; FNEPPK; KRT16A
• Gene ID: 3868
• mRNA Refseq: NM_005557
• Protein Refseq: NP_005548
• Function: protein binding; structural constituent of cytoskeleton

Reviews

06/08/2022

broad applicability make it a valuable asset for a wide range of research endeavors.

02/20/2019

Researchers can rely on the KRT16 Protein to deliver reliable and reproducible results, facilitating robust data interpretation and scientific advancements.

07/25/2017

It has been widely employed in protein electron microscopy structure analysis, where it has demonstrated remarkable efficacy.

Q&As

Are there any genetic mutations associated with KRT16 protein?

Yes, mutations in the KRT16 gene can lead to various dermatological conditions, such as focal palmoplantar keratoderma.

How is KRT16 protein involved in the pathogenesis of psoriasis?

KRT16 is overexpressed in psoriatic skin lesions and plays a role in the abnormal keratinocyte proliferation and differentiation seen in psoriasis.

Can KRT16 protein be used in regenerative medicine applications?

There is growing interest in utilizing KRT16 protein in tissue engineering and regenerative medicine approaches for skin and wound healing.

How is KRT16 protein used in the diagnosis of skin disorders?

KRT16 protein expression can be assessed through immunohistochemistry or molecular techniques to aid in the diagnosis and classification of skin disorders.

How do changes in KRT16 protein expression affect the skin barrier function?

Alterations in KRT16 expression can impact the integrity and function of the skin barrier, leading to increased susceptibility to environmental insults and potential skin disorders.