"KRT8" Related Products

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Recombinant Human KRT8 Protein, MYC/DDK-tagged

Cat.No. : KRT8-42H
Product Overview : Recombinant Human KRT8 Protein was produced by HEK293T expression system. This protein is fused with a MYC/DDK tag at the C-terminal.
Description : This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 53.5 kDa
AA Sequence : MSIRVTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGSSSFSRTSSSRAVVVKKIETRDGKLVSESSDVLPKTRTRPLEQKLISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining.
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at –80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : >50 ug/mL as determined by microplate BCA method
Figure :

Purified recombinant protein KRT8 was analyzed by SDS-PAGE gel and Coomossie Blue Staining.

Gene Name : KRT8 keratin 8 [ Homo sapiens ]
Official Symbol : KRT8
Synonyms : KRT8; keratin 8; keratin, type II cytoskeletal 8; CARD2; CK8; CYK8; K2C8; K8; KO; cytokeratin 8; cytokeratin-8; CK-8;
Gene ID : 3856
mRNA Refseq : NM_001256282
Protein Refseq : NP_001243211
MIM : 148060
UniProt ID : P05787

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