Recombinant Human LDLR Protein, ALA22-ARG788, Tag Free, Biotinylated
Cat.No. : | LDLR-160H |
Product Overview : | Recombinant human LDL receptor protein was developed from HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. The encoded protein is normally bound at the cell membrane, where it binds low density lipoprotein/cholesterol and is taken into the cell. Lysosomes release the cholesterol, which is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | Tag Free |
Protein length : | ALA22-ARG788 |
Conjugation/Label : | Biotin |
Form : | Lyophilised |
Endotoxin : | Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg). |
Notes : | FOR RESEARCH USE ONLY (RUO). |
Storage : | Recombinant LDL receptor can be stored in working aliquots at 2 to 8 centigrade for one month, or at -20 to -70 centigrade for 1 year. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilised from 0.2 μm filtered PBS solution, pH 7.2, 5% Trehalose. |
Gene Name : | LDLR low density lipoprotein receptor [ Homo sapiens (human) ] |
Official Symbol : | LDLR |
Synonyms : | LDLR; low density lipoprotein receptor; low-density lipoprotein receptor; familial hypercholesterolemia; LDL receptor; low-density lipoprotein receptor class A domain-containing protein 3; FH; FHC; LDLCQ2; |
Gene ID : | 3949 |
mRNA Refseq : | NM_000527 |
Protein Refseq : | NP_000518 |
MIM : | 606945 |
UniProt ID : | P01130 |
Products Types
◆ Recombinant Protein | ||
LDLR-422H | Recombinant Human LDLR Protein, MYC/DDK-tagged | +Inquiry |
LDLR-348H | Recombinant Human LDLR Protein, Fc-tagged | +Inquiry |
Ldlr-349M | Recombinant Mouse Ldlr Protein, His-tagged | +Inquiry |
LDLR-344H | Recombinant Human LDLR Protein, His-tagged | +Inquiry |
Ldlr-5024M | Recombinant Mouse Ldlr Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
LDLR-85H | Native Human Lipoprotein | +Inquiry |
◆ Lysates | ||
LDLR-2762MCL | Recombinant Mouse LDLR cell lysate | +Inquiry |
LDLR-2780HCL | Recombinant Human LDLR cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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