Recombinant Human Leukocyte-associated Immunoglobulin-like Receptor 2, His-tagged

• Cat.No.: LAIR2-5586H
• Product Overview: Recombinant humanLAIR2 protein, fused to His-tag at N-terminus, wasexpressed in E. coli and purified by using conventionalchromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: LAIR2 is asecreted, 131 amino acid (aa) protein that contains one IglikeC2 type domain,making it a member of the Ig superfamily. Although one is secreted and one ismembranebound, the two LAIR proteins are thought to have arisen from a commongene ancestor and appear to share similaradhesion profiles. This suggeststhat LAIR2 may compete with LAIR1 for ligand binding.
• Form: Liquid. 20mMTris-HCl buffer (pH 8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT.
• Molecular Weight: 15.2 kDa (139aa) confirmed by MALDI-TOF
• Purity: > 90% by SDS-PAGE
• Concentration: 1 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMQEGAL PRPSISAEPG TVISPGSHVT FMCRGPVGVQTFRLEREDRA KYKDSYNVFR LGPSESEARF HIDSVSEGNA GLYRCLYYKP PGWSEHSDFL ELLVKGTVPGTEASGFDAP
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: LAIR2
• Function: receptor activity

Gene Information

• Gene Name: LAIR2 leukocyte-associatedimmunoglobulin-like receptor 2 [ Homo sapiens ]
• Synonyms: LAIR2; leukocyte-associatedimmunoglobulin-like receptor 2; CD306; MGC71634; leukocyte-associated Ig-likereceptor 2; Leukocyte-associated immunoglobulin-like receptor 2; LAIR-2;CD306 antigen; leukocyte-associated Ig-like receptor-2; OTTHUMP00000174336; OTTHUMP00000174337;OTTHUMP00000068389; OTTHUMP00000068390
• Gene ID: 3904
• mRNA Refseq: NM_002288
• Protein Refseq: NP_002279
• MIM: 602993
• UniProt ID: Q6ISS4
• Chromosome Location: 19q13.4