Recombinant Human LGALS13 Protein (Ser2-Asn139), N-His tagged, Animal-free, Carrier-free

• Cat.No.: LGALS13-133H
• Product Overview: Recombinant Human LGALS13 Protein (Ser2-Asn139) with N-His tag was expressed in E. coli and Animal-free as well as Carrier-free.

Specification

• Description: Galectin-13 (Gal-13) is a lectin family member and is one of the prototype galectins. It contains one carbohydrate recognition domain (CRD), responsible for β-galactoside binding, and is biologically active as homodimers. Galectin-13 is expressed in the placenta, contributing to T cell apoptosis, immune regulation, and immune tolerance, which is indispensable for fetal development. For example, galectin-13 organizes crystal-like aggregates in the decidua, consequently attracting and killing maternal immune cells. Furthermore, galectin-13 is essential for driving neutrophil polarization in the placental-growth-permissive phenotype.
• Source: E. coli
• Species: Human
• Tag: N-His
• Form: Lyophilized
• Molecular Mass: The protein has a calculated MW of 16.9 kDa.
  The protein migrates as 17 kDa under reducing condition (SDS-PAGE analysis).
• Protein Length: Ser2-Asn139
• Endotoxin: < 0.1 EU/μg of the protein by the LAL method.
• Purity: >95% as determined by SDS-PAGE analysis.
• Storage: This product is stable after storage at:
  -20 centigrade for 12 months in lyophilized state from date of receipt.
  -20 or -80 centigrade for 1 month under sterile conditions after reconstitution.
  Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
• Shipping: The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage.

Gene Information

• Gene Name: LGALS13 lectin, galactoside-binding, soluble, 13 [ Homo sapiens (human) ]
• Official Symbol: LGALS13
• Synonyms: LGALS13; lectin, galactoside-binding, soluble, 13; galactoside-binding soluble lectin 13; galectin 13; PLAC8; PP13; gal-13; galectin-13; placental protein 13; placental tissue protein 13; beta-galactoside-binding lectin; GAL13
• Gene ID: 29124
• mRNA Refseq: NM_013268
• Protein Refseq: NP_037400
• MIM: 608717
• UniProt ID: Q9UHV8