Recombinant Human Lgals2, His-tagged

• Cat.No.: Lgals2-7125H
• Product Overview: Recombinant Mouse Lgals2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: Galectin 2, also known as Lgals2, belongs to the galectins family. Galectins are a family of soluble beta-galactoside-binding animal lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. Lgals2 is a monomeric or homodimeric prototype galectin that is expressed in hepatoma, stomach epithelial cells and in colorectal and neural tumors. It induces apoptosis in activated T cells and binds to the cytokine lymphotoxin-a (LTA) with possible implications in risk of myocardial infarction. Human and mouse Lgals2 share approximately 65% amino acid sequence similarity.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol,1mM DTT
• Molecular Mass: 17.3 kDa (153aa)
• Protein length: 1-130aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSEKFEV KDLNMKPGMS LKIKGKIHND VDRFLINLGQ GKETLNLHFN PRFDESTIVC NTSEGGRWGQEQRENHMCFS PGSEVKITIT FQDKDFKVTL PDGHQLTFPN RLGHNQLHYL SMGGLQISSF KLE
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: LGALS2 lectin, galactoside-binding, soluble, 2 [ Homo sapiens ]
• Official Symbol: Lgals2
• Synonyms: LGALS2; lectin, galactoside-binding, soluble, 2; galectin-2; galectin 2; HL14; gal-2; S-Lac lectin 2; lactose-binding lectin 2; beta-galactoside-binding lectin L-14-II; MGC75071
• Gene ID: 3957
• mRNA Refseq: NM_006498
• Protein Refseq: NP_006489
• MIM: 150571
• UniProt ID: P05162
• Chromosome Location: 22q13.1
• Function: galactoside binding; sugar binding