Recombinant Human LGALS3 Protein, His-tagged

• Cat.No.: LGALS3-1089H
• Product Overview: Recombinant Human LGALS3 Protein (Met1-Ile250) with His tag was expressed in 293F.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: Met1-Ile250
• Description: This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 27.8 kDa; Accurate Molecular Mass: 35 kDa
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% SKL, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: LGALS3 galectin 3 [ Homo sapiens (human) ]
• Official Symbol: LGALS3
• Synonyms: LGALS3; galectin 3; L31; GAL3; MAC2; CBP35; GALBP; GALIG; LGALS2; galectin-3; 35 kDa lectin; IgE-binding protein; MAC-2 antigen; advanced glycation end-product receptor 3; carbohydrate-binding protein 35; epididymis secretory sperm binding protein; galactose-specific lectin 3; laminin-binding protein; lectin L-29; lectin, galactoside-binding, soluble, 3
• Gene ID: 3958
• mRNA Refseq: NM_002306
• Protein Refseq: NP_001344607
• MIM: 153619
• UniProt ID: P17931