Recombinant Human LRRC3B Protein, GST-tagged

• Cat.No.: LRRC3B-4668H
• Product Overview: Human LRRC3B full-length ORF ( NP_443185.1, 1 a.a. - 259 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 55.7 kDa
• AA Sequence: MNLVDLWLTRSLSMCLLLQSFVLMI LCFHSASMCPKGCLCSSSGGLNVTC SNANLKEIPRDLPPETVLLYLDSNQ ITSIPNEIFKDLHQLRVLNLSKNGI EFIDEHAFKGVAETLQTLDLSDNRI QSVHKNAFNNLKARARIANNPWHCD CTLQQVLRSMASNHETAHNVICKTS VLDEHAGRPFLNAANDADLCNLPKK TTDYAMLVTMFGWFTMVISYVVYYV RQNQEDARRHLEYLKSLPSRQKKAD EPDDISTVV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: LRRC3B leucine rich repeat containing 3B [ Homo sapiens ]
• Official Symbol: LRRC3B
• Synonyms: LRP15; LRRC3B; leucine rich repeat containing 3B
• Gene ID: 116135
• mRNA Refseq: NM_052953
• Protein Refseq: NP_443185
• UniProt ID: Q96PB8