Recombinant Human Lymphotoxin Alpha (TNF superfamily, member 2), His-tagged
Cat.No. : | LTA-5068H |
- Specification
- Gene Information
- Related Products
Cat. No. : | LTA-5068H |
roduct Overview : | Recombinant LTAprotein was expressed in E. coli and purified by using conventionalchromatography techniques. |
Description : | LTA, a member of thetumor necrosis factor family, is a cytokine produced by lymphocytes. Theprotein is highly inducible, secreted, and forms heterotrimers withlymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. Thisprotein also mediates a large variety of inflammatory, immunostimulatory, andantiviral responses, is involved in the formation of secondary lymphoidorgans during development and plays a role in apoptosis. |
Concentration : | 0.5 mg/ml |
Source : | Human |
Host : | E. coli |
Form : | Suppliedas a liquid in 20mM Tris-HCl buffer, pH 8.0, containing 30% glycerol, 0.1MNaCl, and 1mM DTT. |
Purity : | > 90% by SDS -PAGE |
Sequence : | 35-205 amino acids:MGSSHHHHHH SSGLVPRGSH MLPGVGLTPS AAQTARQHPK MHLAHSTLKP AAHLIGDPSK QNSLLWRANTDRAFLQDGFS LSNNSLLVPT SGIYFVYSQV VFSGKAYSPK ATSSPLYLAH EVQLFSSQYP FHVPLLSSQKMVYPGLQEPW LHSMYHGAAF QLTQGDQLST HTDGIPHLVL SPSTVFFGAF AL |
Molecular Mass : | 20.9 kDa(192aa), confirmed by MALDI-TOF. |
Applications : | SDS-PAGE |
Storage : | Storeat 4 deg C for short term storage (1/2 weeks). Aliquot and store at -20 deg Cor - 70 deg C for long term storage. Avoid repeated freeze/thaw cycles. |
OfficialSymbol : | LTA |
Gene Name : | LTAlymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ] |
Synonyms : | LTA; lymphotoxin alpha (TNF superfamily, member 1); LT; TNFB;TNFSF1; lymphotoxin-alpha; LT-alpha; TNF-beta; OTTHUMP00000029184;OTTHUMP00000165897; tumor necrosis factor beta; tumor necrosis factor ligandsuperfamily member 1 |
Gene ID : | 4049 |
mRNA Refseq : | NM_000595 |
Protein Refseq : | NP_000586 |
MIM : | 153440 |
UniProt ID : | P01374 |
Chromosome Location : | 6p21.3 |
Pathway : | Apoptosis;Cytokine-cytokine receptor interaction; HTLV-I infection; Herpes simplexinfection; IL2 signaling events mediated by STAT5; IL4-mediated signaling events;Type I diabetes mellitus |
Function : | cytokineactivity; receptor binding; tumor necrosis factor receptor binding |
Products Types
◆ Native Protein | ||
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◆ Lysates | ||
LTA-9167HCL | Recombinant Human LTA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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