Recombinant Human MAF
Cat.No. : | MAF-26878TH |
Product Overview : | Recombinant fragment of Human c-Maf with N terminal proprietary tag; predicted MWt: 36.63 kDa including the tag. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Expressed in endothelial cells. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | SCRFKRVQQRHVLESEKNQLLQQVD HLKQEISRLVRERDAYKEKYEKLVS SGFRENGSSSDNPSSPEFFITEPTR KLEPSVGYATFWKPQHRVLTSVFTK |
Sequence Similarities : | Belongs to the bZIP family. Maf subfamily.Contains 1 bZIP domain. |
Gene Name : | MAF v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian) [ Homo sapiens ] |
Official Symbol : | MAF |
Synonyms : | MAF; v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian); v maf musculoaponeurotic fibrosarcoma (avian) oncogene homolog; transcription factor Maf; c MAF; |
Gene ID : | 4094 |
mRNA Refseq : | NM_001031804 |
Protein Refseq : | NP_001026974 |
MIM : | 177075 |
Uniprot ID : | O75444 |
Chromosome Location : | 16q22-q23 |
Pathway : | C-MYB transcription factor network, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Keap1-Nrf2 Pathway, organism-specific biosystem; Transcriptional misregulation in cancers, organism-specific biosystem; Transcriptional misregulation in cancers, conserved biosystem; |
Function : | sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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