Recombinant Human MAP3K1 Protein, MYC/DDK-tagged
Cat.No. : | MAP3K1-393H |
Product Overview : | Recombinant human MAP3K1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293. |
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Description : | The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus. [provided by RefSeq, Mar 2012]. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol. |
Molecular Mass : | 164.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | mitogen-activated protein kinase kinase kinase 1 [ Homo sapiens ] |
Official Symbol : | MAP3K1 |
Synonyms : | MAPKKK1; MEKK; MEKK 1; MEKK1; SRXY6 |
Gene ID : | 4214 |
mRNA Refseq : | NM_005921.1 |
Protein Refseq : | NP_005912.1 |
MIM : | 600982 |
UniProt ID : | Q13233 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionMAP3K1 protein expression can be measured using immunohistochemistry (IHC) or Western blotting in clinical settings.
Yes, mutations in the MAP3K1 gene have been linked to several diseases, including breast cancer, lung cancer, and colon cancer.
MAP3K1 protein has been implicated in the development of drug resistance in certain cancer types, highlighting its importance in personalized medicine and treatment response.
MAP3K1 protein analysis can be used for diagnostic purposes to identify specific molecular subtypes of cancer and to predict disease prognosis.
Precision medicine approaches may involve targeting MAP3K1 protein through specific inhibitors or monoclonal antibodies to inhibit its oncogenic activity.
Customer Reviews (3)
Write a reviewThe bands of proteins in Western Blotting experiments were very clear.
The MAP3K1 protein is highly recommended for its exceptional performance in ELISA assays.
Researchers can rely on the MAP3K1 protein to deliver precise results, enhancing the credibility and efficiency of their experiments.
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