Recombinant Human MBNL1

• Cat.No.: MBNL1-30258TH
• Product Overview: Recombinant full length Human Muscleblind-like 1 according to AAH50535,with N-terminal proprietary tag.Mol Wt 63.84 kDa inclusive of tag.

Specification

• Description: Muscleblind-like (Drosophila), also known as MBNL1, is a protein that in humans is encoded by the MBNL1 gene. It has been implicated in Myotonic dystrophy and has been shown to autoregulate its transcript.
• Protein length: 343 amino acids
• Molecular Weight: 63.840kDa inclusive of tags
• Source: Wheat germ
• Tissue specificity: Highly expressed in cardiac, skeletal muscle and during myoblast differentiation. Weakly expressed in other tissues (at protein level). Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
• Form: Liquid
• Purity: Proprietary Purification
• Storage buffer: pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
• Storage: Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MGRCSRENCKYLHPPPHLKTQLEINGRNNLIQQKNMAMLA QQMQLANAMMPGAPLQPVPMFSVAPSLATNASAAAFNPYL GPVSPSLVPAEILPTAPMLVTGNPGVPVPAAAAAAAQKLM RTDRLEVCREYQRGNCNRGENDCRFAHPADSTMIDTNDNT VTVCMDYIKGRCSREKCKYFHPPAHLQAKIKAAQYQVNQA AAAQAAATAAAMTQSAVKSLKRPLEATFDLGIPQAVLPPL PKRPALEKTNGATAVFNTGIFQYQQALANMQLQQHTAFLP PGSILCMTPATSVVPMVHGATPATVSAATTSATSVPFAAT ATANQIPIISAEHLTSHKYVTQM
• Sequence Similarities: Belongs to the muscleblind family.Contains 4 C3H1-type zinc fingers.

Gene Information

• Gene Name: MBNL1 muscleblind-like (Drosophila) [ Homo sapiens ]
• Official Symbol: MBNL1
• Synonyms: MBNL1; muscleblind-like (Drosophila); MBNL, muscleblind (Drosophila) like; muscleblind-like protein 1; EXP; EXP35; EXP40; EXP42; KIAA0428
• Gene ID: 4154
• mRNA Refseq: NM_207294
• Protein Refseq: NP_997177
• MIM: 606516
• Uniprot ID: Q9NR56
• Chromosome Location: 3q25
• Pathway: Adipogenesis, organism-specific biosystem
• Function: RNA binding; double-stranded RNA binding; metal ion binding; nucleic acid binding; protein binding