Recombinant Human MICA protein, His-Avi-tagged

• Cat.No.: MICA-964H
• Product Overview: Recombinant Human MICA Protein is expressed from mammalian with His and Avi Tag at the C-terminal. It contains Ala23-Gln308.

Specification

• Description: MICA (MHC class I chain-related gene A) is a transmembrane glycoprotein that functions as a ligand for human NKG2D. A closely related protein, MICB, shares 85% amino acid identity with MICA. These proteins are distantly related to the MHC class I proteins. They possess three extracellular Ig‑like domains, but they have no capacity to bind peptide or interact with beta 2-microglobulin.
• Source: HEK293
• Species: Human
• Tag: His-Avi
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 35.8KDa. Due to glycosylation, the protein migrates to 55-70KDa based on Bis-Tris PAGE result.
• Protein length: Ala23-Gln308
• Endotoxin: Less than 0.2 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: MICA MHC class I polypeptide-related sequence A [ Homo sapiens (human) ]
• Official Symbol: MICA
• Synonyms: FLJ60820; MGC111087; MICA; PERB11.1; Stress inducible class I homolog; MHC class I polypeptide-related sequence A, isoform CRA_
• Gene ID: 100507436
• mRNA Refseq: NM_001177519.3
• Protein Refseq: NP_001170990.1
• MIM: 600169
• UniProt ID: Q96QC4