Recombinant Human MMP8 protein, His&Myc-tagged

• Cat.No.: MMP8-1243H
• Product Overview: Recombinant Human MMP8 protein(P22894)(101-467aa), fused with N-terminal His tag and C-terminal Myc tag, was expressed in E.coli.

Specification

• Source: E.coli
• Species: Human
• Tag: N-His&C-Myc
• Protein length: 101-467aa
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 49.4 kDa
• AASequence: LTPGNPKWERTNLTYRIRNYTPQLS EAEVERAIKDAFELWSVASPLIFTR ISQGEADINIAFYQRDHGDNSPFDG PNGILAHAFQPGQGIGGDAHFDAEE TWTNTSANYNLFLVAAHEFGHSLGL AHSSDPGALMYPNYAFRETSNYSLP QDDIDGIQAIYGLSSNPIQPTGPST PKPCDPSLTFDAITTLRGEILFFKD RYFWRRHPQLQRVEMNFISLFWPSL PTGIQAAYEDFDRDLIFLFKGNQYW ALSGYDILQGYPKDISNYGFPSSVQ AIDAAVFYRSKTYFFVNDQFWRYDN QRQFMEPGYPKSISGAFPGIESKVD AVFQQEHFFHVFSGPRYYAFDLIAQ RVTRVARGNKWLNCRYG
• Purity: Greater than 90% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C.

Gene Information

• Gene Name: MMP8 matrix metallopeptidase 8 (neutrophil collagenase) [ Homo sapiens ]
• Official Symbol: MMP8
• Synonyms: MMP8; matrix metallopeptidase 8 (neutrophil collagenase); CLG1, matrix metalloproteinase 8 (neutrophil collagenase); neutrophil collagenase; PMNL collagenase; matrix metalloproteinase-8; matrix metalloproteinase 8 (neutrophil collagenase); HNC; CLG1; MMP-8; PMNL-CL
• Gene ID: 4317
• mRNA Refseq: NM_002424
• Protein Refseq: NP_002415
• MIM: 120355
• UniProt ID: P22894

Reviews

04/03/2022

The use of MMP8 as a catalyst can significantly increase the rate and yield of chemical reactions with impressive high catalytic efficiency.

09/14/2021

MMP8 is really impressive, the results of every experiment are very consistent, you can see that its production process is very careful.

03/20/2021

MMP8 are inexpensive to prepare and cost-effective, making them ideal for our study.

Q&As

What signaling pathways does the MMP8 protein interact with?

The MMP8 protein interacts with a variety of signaling pathways, including TNF-α, TGF-β, Wnt, and NF-κB.

What drugs interact with the MMP8 protein?

A number of inhibitors and modulators of MMP8 protein have been developed for the regulation of MMP8 activity and the treatment of related diseases.

Why does MMP8 protein play a role in tissue repair?

The MMP8 protein is involved in the tissue repair and wound healing process, by degrading damaged tissue and supporting the formation of new tissue.

What is the mechanism of action of MMP8 protein in inflammatory response?

MMP8 protein is involved in regulating the production of inflammation-related molecules and cell infiltration, promoting the occurrence and maintenance of inflammatory response.

Does MMP8 have a role in post-traumatic recovery?

MMP8 protein is involved in the inflammatory and remodeling processes of post-traumatic wound healing, contributing to wound repair and tissue regeneration.

Does the MMP8 protein study have implications for new drug development?

MMP8 protein plays an important role in the occurrence and progression of diseases, and studying the regulatory mechanism of MMP8 protein is helpful for the development of new drugs, such as inhibitors targeting MMP8 protein may be applied to the treatment of related diseases