Recombinant Human MR1 Protein, Myc/DDK-tagged

• Cat.No.: MR1-01H
• Product Overview: Recombinant protein of human major histocompatibility complex, class I-related (MR1) with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Description: MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.
• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 39.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: MR1 major histocompatibility complex, class I-related [ Homo sapiens (human) ]
• Official Symbol: MR1
• Synonyms: MR1; major histocompatibility complex, class I-related; HLALS; major histocompatibility complex class I-related gene protein; MHC class I-like antigen MR-1; MHC class-I related-gene protein; major histocompatibility complex, class I-like sequence
• Gene ID: 3140
• mRNA Refseq: NM_001531
• Protein Refseq: NP_001522
• MIM: 600764
• UniProt ID: Q95460

Reviews

04/03/2023

The high purity of MR1 reduces impurity interference in the experiment.

03/21/2023

The assay is very sensitive and allows for easy detection of trace amounts of protein.

08/18/2021

The colleagues around me were full of praise, and the experimental effect was too good.

Q&As

What are the implications of changes in MR1 levels for the diagnosis and prognosis of the disease?

Changes in MR1 levels may be useful for early diagnosis of the disease, monitoring of disease progression, and assessment of prognosis. By monitoring changes in MR1 levels, doctors can better understand the patient's disease status and develop a treatment plan accordingly.

What treatments are available to modulate MR1 levels?

There may not be a specific treatment that directly targets the regulation of MR1 levels. However, treatments for diseases or conditions associated with MR1 may indirectly affect MR1 levels. The specific treatment plan should be determined based on the patient's specific situation and the doctor's recommendation.

What diseases or conditions are associated with abnormal levels of MR1?

Abnormal levels of MR1 may be associated with increased risk, disease progression, or poor prognosis for a particular disease or condition. Specific disease associations need to be determined based on available clinical research and evidence.

How can I distinguish between MR1 levels and disease?

Distinguishing between MR1 levels and disease requires in-depth research and analysis. Through clinical trials, epidemiological studies, and other relevant research methods, the strength of the association between changes in MR1 levels and the occurrence and progression of the disease can be determined.

How can I detect the level of MR1?

Measuring MR1 levels usually requires the use of specific biotechnological methods such as blood tests, tissue sample analysis, or other body fluid testing methods. These methods allow for quantitative or qualitative analysis of MR1.

What factors may affect the level of MR1?

The level of MR1 may be affected by a variety of factors, including age, gender, genetic factors, environmental factors, lifestyle, etc. Understanding these influencing factors can help to interpret changes in MR1 levels more accurately.