Recombinant Human MRE11A Protein, His-tagged
Cat.No. : | MRE11A-741H |
Product Overview : | Recombinant Human MRE11A, transcript variant 2, fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Molecular Mass : | 77.5 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name : | MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae) [ Homo sapiens ] |
Official Symbol : | MRE11A |
Synonyms : | MRE11A; MRE11 meiotic recombination 11 homolog A (S. cerevisiae); meiotic recombination (S. cerevisiae) 11 homolog A , MRE11; double-strand break repair protein MRE11A; AT like disease; ATLD; AT-like disease; MRE11 homolog 1; MRE11 homolog A; endo/exonuclease Mre11; meiotic recombination 11 homolog 1; meiotic recombination 11 homolog A; DNA recombination and repair protein; HNGS1; MRE11; MRE11B; |
Gene ID : | 4361 |
mRNA Refseq : | NM_005590 |
Protein Refseq : | NP_005581 |
MIM : | 600814 |
UniProt ID : | P49959 |
Products Types
◆ Recombinant Protein | ||
MRE11A-3407R | Recombinant Rat MRE11A Protein, His (Fc)-Avi-tagged | +Inquiry |
MRE11A-5537H | Recombinant Human MRE11A Protein, GST-tagged | +Inquiry |
Mre11a-4136M | Recombinant Mouse Mre11a Protein, Myc/DDK-tagged | +Inquiry |
MRE11A-6342C | Recombinant Chicken MRE11A | +Inquiry |
MRE11A-212Z | Recombinant Zebrafish MRE11A | +Inquiry |
◆ Lysates | ||
MRE11A-4211HCL | Recombinant Human MRE11A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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