Recombinant Human MRNIP Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: MRNIP-4642H
• Product Overview: C5orf45 MS Standard C13 and N15-labeled recombinant protein (NP_057259) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Plays a role in the cellular response to DNA damage and the maintenance of genome stability through its association with the MRN damage-sensing complex. Promotes chromatin loading and activity of the MRN complex to facilitate subsequent ATM-mediated DNA damage response signaling and DNA repair.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 37.6 kDa
• AA Sequence: MASLQRSRVLRCCSCRLFQAHQVKK SVKWTCKACGEKQSFLQAYGEGSGA DCRRHVQKLNLLQGQVSELPLRSLE ETVSASEEENVGHQQAGNVKQQEKS QPSESRWLKYLEKDSQELELEGTGV CFSKQPSSKMEEPGPRFSQDLPRKR KWSGSTVQPPCSRGVQDSGGSEVAW GPQKGQAGLTWKVKQGSSPCLQENS ADCSAGELRGPGKELWSPIQQVTAT SSKWAQFVLPPRKSSHVDSEQPRSL QRDPRPAGPAQAKQGTPRAQASREG LSRPTAAVQLPRATHPVTSGSERPC GKTSWDARTPWAEGGPLVLEAQNPR PTRLCDLFITGEDFDDDVTRTRPLE QKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: MRNIP MRN complex interacting protein [ Homo sapiens (human) ]
• Official Symbol: MRNIP
• Synonyms: MRNIP; MRN complex interacting protein; C5orf45; MRN complex-interacting protein; MRN-interacting protein; UPF0544 protein C5orf45
• Gene ID: 51149
• mRNA Refseq: NM_016175
• Protein Refseq: NP_057259
• MIM: 617154
• UniProt ID: Q6NTE8