Recombinant Human MSH4 Protein, GST-tagged MSH4-5651H

Recombinant Human MSH4 Protein, GST-tagged

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Recombinant Human MSH4 Protein, GST-tagged

MSH4 Related Products

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Cat.No. : MSH4-5651H
Product Overview : Human MSH4 partial ORF ( NP_002431, 831 a.a. - 936 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. [provided by RefSeq, Aug 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 37.4 kDa
AA Sequence : YKLSKGLTEEKNYGL KAAEVSSLPPSIVLD AKEITTQITRQILQN QRSTPEMERQRAVYH LATRLVQTARNSQLD PDSLRIYLSNLKKKY KEDFPRTEQVPEKTE E
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : MSH4 mutS homolog 4 (E. coli) [ Homo sapiens ]
Official Symbol : MSH4
Synonyms : MSH4; mutS homolog 4 (E. coli); mutS (E. coli) homolog 4; mutS protein homolog 4; hMSH4;
Gene ID : 4438
mRNA Refseq : NM_002440
Protein Refseq : NP_002431
MIM : 602105
UniProt ID : O15457

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