Recombinant Human MSH4 Protein, GST-tagged

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Recombinant Human MSH4 Protein, GST-tagged

MSH4 Related Products

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Cat.No. : MSH4-5651H
Product Overview : Human MSH4 partial ORF ( NP_002431, 831 a.a. - 936 a.a.) recombinant protein with GST-tag at N-terminal.
Description : This gene encodes a member of the DNA mismatch repair mutS family. This member is a meiosis-specific protein that is not involved in DNA mismatch correction, but is required for reciprocal recombination and proper segregation of homologous chromosomes at meiosis I. This protein and MSH5 form a heterodimer which binds uniquely to a Holliday Junction and its developmental progenitor, thus provoking ADP-ATP exchange, and stabilizing the interaction between parental chromosomes during meiosis double-stranded break repair. [provided by RefSeq, Aug 2011]
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 37.4 kDa
AA Sequence : YKLSKGLTEE KNYGLKAAEV SSLPPSIVLD AKEITTQITR QILQNQRSTP EMERQRAVYH LATRLVQTAR NSQLDPDSLR IYLSNLKKKY KEDFPRTEQV PEKTEE
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing: :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : MSH4 mutS homolog 4 (E. coli) [ Homo sapiens ]
Official Symbol : MSH4
Synonyms : MSH4; mutS homolog 4 (E. coli); mutS (E. coli) homolog 4; mutS protein homolog 4; hMSH4;
Gene ID : 4438
mRNA Refseq : NM_002440
Protein Refseq : NP_002431
MIM : 602105
UniProt ID : O15457
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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