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Recombinant Human MSTN, His-tagged

Cat.No. : MSTN-119H
Product Overview : Recombinant Human MSTN(total 152AA.), fused with N-terminal His-tag, was expressed in E.Coli.
  • Specification
  • Gene Information
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Description : The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
Source : E.Coli
Species : Human
Tag : His
Form : Filtered white lyophilized (freeze-dried) powder. Filtered (0.4µm) and lyophilized from 0.5 mg/ml in 0.05M acetate buffer, pH 4.5.
Molecular Mass : 16.7kDa (calculated)
AA Sequence : MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDPSSRSAVR SRRDFGLDCD EHSTESRCCR YPLTVDFEAFGWDWIIAPKR YKANYCSGEC EFVFLQKYPH THLVHQANPR GSAGPCCTPT KMSPINMLYF NGKEQIIYGKIPAMVVDRCG CS.
Purity : Greater than 95% as determined by SDS-PAGE.
Stability : Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Concentration : Add 0.1M Acetate buffer pH-4 to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10μg/ml. In higher concentrations the solubility of this antigen is limited.
Gene Name : MSTN myostatin [ Homo sapiens (human) ]
Official Symbol : MSTN
Synonyms : MSTN; myostatin; GDF8; MSLHP; growth/differentiation factor 8; GDF-8; growth differentiation factor 8
Gene ID : 2660
mRNA Refseq : NM_005259
Protein Refseq : NP_005250
MIM : 601788
UniProt ID : O14793
Chromosome Location : 2q32.2
Pathway : Hypertrophy Model
Function : cytokine activity; growth factor ; heparin binding; identical protein binding

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