Recombinant Human MYB Protein, GST-tagged

• Cat.No.: MYB-5777H
• Product Overview: Human MYB full-length ORF ( NP_005366.2, 1 a.a. - 640 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 98.7 kDa
• AA Sequence: MARRPRHSIYSSDEDDEDFEMCDHD YDGLLPKSGKRHLGKTRWTREEDEK LKKLVEQNGTDDWKVIANYLPNRTD VQCQHRWQKVLNPELIKGPWTKEED QRVIELVQKYGPKRWSVIAKHLKGR IGKQCRERWHNHLNPEVKKTSWTEE EDRIIYQAHKRLGNRWAEIAKLLPG RTDNAIKNHWNSTMRRKVEQEGYLQ ESSKASQPAVATSFQKNSHLMGFAQ APPTAQLPATGQPTVNNDYSYYHIS EAQNVSSHVPYPVALHVNIVNVPQP AAAAIQRHYNDEDPEKEKRIKELEL LLMSTENELKGQQVLPTQNHTCSYP GWHSTTIADHTRPHGDSAPVSCLGE HHSTPSLPADPGSLPEESASPARCM IVHQGTILDNVKNLLEFAETLQFID SFLNTSSNHENSDLEMPSLTSTPLI GHKLTVTTPFHRDQTVKTQKENTVF RTPAIKRSILESSPRTPTPFKHALA AQEIKYGPLKMLPQTPSHLVEDLQD VIKQESDESGIVAEFQENGPPLLKK IKQEVESPTDKSGNFFCSHHWEGDS LNTQLFTQTSPVADAPNILTSSVLM APASEDEDNVLKAFTVPKNRSLASP LQPCSSTWEPASCGKMEEQMTSSSQ ARKYVNAFSARTLVM
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MYB v-myb myeloblastosis viral oncogene homolog (avian) [ Homo sapiens ]
• Official Symbol: MYB
• Synonyms: MYB; v-myb myeloblastosis viral oncogene homolog (avian); v myb avian myeloblastosis viral oncogene homolog; transcriptional activator Myb; c myb; c-myb8B_CDS; c-myb10A_CDS; c-myb13A_CDS; c-myb14A_CDS; proto-oncogene c-Myb; c-myb protein (140 AA); efg; Cmyb; c-myb; c-myb_CDS
• Gene ID: 4602
• mRNA Refseq: NM_001130172
• Protein Refseq: NP_001123644
• MIM: 189990
• UniProt ID: P10242