Recombinant Human MYD88 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Recombinant Human MYD88 Protein, MYC/DDK-tagged, C13 and N15-labeled

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Cat.No. : MYD88-272H
Product Overview : MYD88 MS Standard C13 and N15-labeled recombinant protein (NP_002459) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 33.2 kDa
AA Sequence : MAAGGPGAGS AAPVSSTSSL PLAALNMRVR RRLSLFLNVR TQVAADWTAL AEEMDFEYLE IRQLETQADP TGRLLDAWQG RPGASVGRLL ELLTKLGRDD VLLELGPSIE EDCQKYILKQ QQEEAEKPLQ VAAVDSSVPR TAELAGITTL DDPLGHMPER FDAFICYCPS DIQFVQEMIR QLEQTNYRLK LCVSDRDVLP GTCVWSIASE LIEKRCRRMV VVVSDDYLQS KECDFQTKFA LSLSPGAHQK RLIPIKYKAM KKEFPSILRF ITVCDYTNPC TKSWFWTRLA KALSLPTRTR PLEQKLISEE DLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : MYD88 myeloid differentiation primary response gene (88) [ Homo sapiens (human) ]
Official Symbol : MYD88
Synonyms : MYD88; myeloid differentiation primary response gene (88); myeloid differentiation primary response protein MyD88; MYD88D;
Gene ID : 4615
mRNA Refseq : NM_002468
Protein Refseq : NP_002459
MIM : 602170
UniProt ID : Q99836

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