Recombinant Human Myosin, Light Chain 7, Regulatory, His-tagged

• Cat.No.: MYL7-6780H
• Product Overview: Recombinant humanMYL7 protein, fused to His-tag at N-terminus, was expressed in E.coli andpurified by using conventional chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: MYL7 protein is aatrial isoform of myosin regulatory light chain 2(MYL2). Myosin is an hexamerof 2 heavy chains and 4 light chains. MYL7 is predominantly expressed inadult atrial muscle
• Form: 20mM Tris-HCl buffer(pH8.0) containing 20% glycerol, 0.1M NaCl, 1mM DTT
• Molecular Weight: 22.0 kDa (199aa),confirmed by MALDI-TOF
• Purity: > 90% by SDS -PAGE
• Concentration: 0.5 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MGSHMASRKA GTRGKVAATK QAQRGSSNVF SMFEQAQIQE FKEAFSCIDQ NRDGIICKADLRETYSQLGK VSVPEEELDA MLQEGKGPIN FTVFLTLFGE KLNGTDPEEA ILSAFRMFDP SGKGVVNKDEFKQLLLTQAD KFSPAEVEQM FALTPMDLAG NIDYKSLCYI ITHGDEKEE
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: MYL7myosin, light chain 7, regulatory [ Homo sapiens ]
• Official Symbol: MYL7
• Synonyms: MYL7; myosin, light chain 7,regulatory; myosin, light polypeptide 7, regulatory; myosin regulatory lightchain 2, atrial isoform; MYL2A; MYLC2A; atrial isoform; MLC-2a; MLC2a;MLRA_HUMAN; MYL7; Mylc2a; Myosin light chain 2a; Myosin regulatory lightchain 2; Myosin regulatory light chain 2, atrial isoform; Myosin regulatorylight chain 7; MLC2a; MLC-2a; myosin light chain 2a; myosin regulatory lightchain 7
• Gene ID: 58498
• mRNA Refseq: NM_021223
• Protein Refseq: NP_067046
• MIM: 613993
• Uniprot ID: Q01449
• Chromosome Location: 7p21-p11.2
• Pathway: Focal adhesion, organism-specificbiosystem; Focal adhesion, conserved biosystem; Leukocyte transendothelialmigration, organism-specific biosystem; Leukocyte transendothelial migration,conserved biosystem; Regulation of actin cytoskeleton, organism-specificbiosystem
• Function: ATPase activity, coupled; calciumion binding; microfilament motor activity