Recombinant Human NEU3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NEU3-4603H
• Product Overview: NEU3 MS Standard C13 and N15-labeled recombinant protein (NP_006647) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene product belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. It is localized in the plasma membrane, and its activity is specific for gangliosides. It may play a role in modulating the ganglioside content of the lipid bilayer.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 52.1 kDa
• AA Sequence: MRPADLPPRPMEESPASSSAPTETE EPGSSAEVMEEVTTCSFNSPLFRQE DDRGITYRIPALLYIPPTHTFLAFA EKRSTRRDEDALHLVLRRGLRIGQL VQWGPLKPLMEATLPGHRTMNPCPV WEQKSGCVFLFFICVRGHVTERQQI VSGRNAARLCFIYSQDAGCSWSEVR DLTEEVIGSELKHWATFAVGPGHGI QLQSGRLVIPAYTYYIPSWFFCFQL PCKTRPHSLMIYSDDLGVTWHHGRL IRPMVTVECEVAEVTGRAGHPVLYC SARTPNRCRAEALSTDHGEGFQRLA LSRQLCEPPHGCQGSVVSFRPLEIP HRCQDSSSKDAPTIQQSSPGSSLRL EEEAGTPSESWLLYSHPTSRKQRVD LGIYLNQTPLEAACWSRPWILHCGP CGYSDLAALEEEGLFGCLFECGTKQ ECEQIAFRLFTHREILSHLQGDCTS PGRNPSQFKSNTRTRPLEQKLISEE DLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NEU3 neuraminidase 3 [ Homo sapiens (human) ]
• Official Symbol: NEU3
• Synonyms: NEU3; sialidase 3 (membrane sialidase); sialidase-3; neuraminidase 3; membrane sialidase; ganglioside sialidase; N-acetyl-alpha-neuraminidase 3; SIAL3; FLJ12388
• Gene ID: 10825
• mRNA Refseq: NM_006656
• Protein Refseq: NP_006647
• MIM: 604617
• UniProt ID: Q9UQ49