Recombinant Human NFATC2 Protein, MYC/DDK-tagged, C13 and N15-labeled

Cat.No. : NFATC2-391H
Product Overview : NFATC2 MS Standard C13 and N15-labeled recombinant protein (NP_001129493) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized. [provided by RefSeq, Apr 2012]
Source : HEK293
Species : Human
Tag : Myc&DDK
Molecular Mass : 97.5 kDa
AA Sequence : MQREAAFRLGHCHPLRIMGSVDQEE PNAHKVASPPSGPAYPDDVLDYGLK PYSPLASLSGEPPGRFGEPDRVGPQ KFLSAAKPAGASGLSPRIEITPSHE LIQAVGPLRMRDAGLLVEQPPLAGV AASPRFTLPVPGFEGYREPLCLSPA SSGSSASFISDTFSPYTSPCVSPNN GGPDDLCPQFQNIPAHYSPRTSPIM SPRTSLAEDSCLGRHSPVPRPASRS SSPGAKRRHSCAEALVALPPGASPQ RSRSPSPQPSSHVAPQDHGSPAGYP PVAGSAVIMDALNSLATDSPCGIPP KMWKTSPDPSPVSAAPSKAGLPRHI YPAVEFLGPCEQGERRNSAPESILL VPPTWPKPLVPAIPICSIPVTASLP PLEWPLSSQSGSYELRIEVQPKPHH RAHYETEGSRGAVKAPTGGHPVVQL HGYMENKPLGLQIFIGTADERILKP HAFYQVHRITGKTVTTTSYEKIVGN TKVLEIPLEPKNNMRATIDCAGILK LRNADIELRKGETDIGRKNTRVRLV FRVHIPESSGRIVSLQTASNPIECS QRSAHELPMVERQDTDSCLVYGGQQ MILTGQNFTSESKVVFTEKTTDGQQ IWEMEATVDKDKSQPNMLFVEIPEY RNKHIRTPVKVNFYVINGKRKRSQP QHFTYHPVPAIKTEPTDEYDPTLIC SPTHGGLGSQPYYPQHPMVAESPSC LVATMAPCQQFRTGLSSPDARYQQQ NPAAVLYQRSKSLSPSLLGYQQPAL MAAPLSLADAHRSVLVHAGSQGQSS ALLHPSPTNQQASPVIHYSPTNQQL RCGSHQEFQHIMYCENFAPGTTRPG PPPVSQGQRLSPGSYPTVIQQQNAT SQRAAKNGPPVSDQKEVLPAGVTIK QEQNLDQTYLDDELIDTHLSWIQNI LTRTRPLEQKLISEEDLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 [ Homo sapiens (human) ]
Official Symbol : NFATC2
Synonyms : NFATC2; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2; nuclear factor of activated T-cells, cytoplasmic 2; NF ATP; NFAT1; NFATp; NF-ATc2; NFAT pre-existing subunit; T cell transcription factor NFAT1; T-cell transcription factor NFAT1; NFAT transcription complex, preexisting component; preexisting nuclear factor of activated T-cells 2; nuclear factor of activated T-cells, preexisting component; NFATP;
Gene ID : 4773
mRNA Refseq : NM_001136021
Protein Refseq : NP_001129493
MIM : 600490
UniProt ID : Q13469

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