Recombinant Human NFKB1 Protein (Met248-Ile366), His tagged
Cat.No. : | NFKB1-2816H |
Product Overview : | Recombinant human NFkB1 (Met248-Ile366) protein fused with His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo-or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by interactions with other cofactors or corepressors. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Molecular Mass : | 102.87 kDa |
Protein Length : | Met248-Ile366 |
Purity : | >90 % as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 [ Homo sapiens (human) ] |
Official Symbol : | NFKB1 |
Synonyms : | NFKB1; nuclear factor of kappa light polypeptide gene enhancer in B-cells 1; nuclear factor NF-kappa-B p105 subunit; KBF1; NF kappaB; NF kB1; NFkappaB; NFKB p50; p50; p105; NF-kappabeta; DNA binding factor KBF1; DNA-binding factor KBF1; nuclear factor NF-kappa-B p50 subunit; nuclear factor kappa-B DNA binding subunit; EBP-1; NF-kB1; NFKB-p50; NF-kappaB; NFKB-p105; NF-kappa-B; MGC54151; DKFZp686C01211; |
Gene ID : | 4790 |
mRNA Refseq : | NM_001165412 |
Protein Refseq : | NP_001158884 |
MIM : | 164011 |
UniProt ID : | P19838 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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