Recombinant Human NFKBIA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: NFKBIA-3784H
• Product Overview: NFKBIA MS Standard C13 and N15-labeled recombinant protein (NP_065390) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 35.4 kDa
• AA Sequence: MFQAAERPQEWAMEGPRDGLKKERL LDDRHDSGLDSMKDEEYEQMVKELQ EIRLEPQEVPRGSEPWKQQLTEDGD SFLHLAIIHEEKALTMEVIRQVKGD LAFLNFQNNLQQTPLHLAVITNQPE IAEALLGAGCDPELRDFRGNTPLHL ACEQGCLASVGVLTQSCTTPHLHSI LKATNYNGHTCLHLASIHGYLGIVE LLVSLGADVNAQEPCNGRTALHLAV DLQNPDLVSLLLKCGADVNRVTYQG YSPYQLTWGRPSTRIQQQLGQLTLE NLQMLPESEDEESYDTESEFTEFTE DELPYDDCVFGGQRLTLTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: NFKBIA NFKB inhibitor alpha [ Homo sapiens (human) ]
• Official Symbol: NFKBIA
• Synonyms: NFKBIA; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; NFKBI; NF-kappa-B inhibitor alpha; IkappaBalpha; IKBA; MAD 3; ikB-alpha; I-kappa-B-alpha; nuclear factor of kappa light chain gene enhancer in B-cells; major histocompatibility complex enhancer-binding protein MAD3; MAD-3
• Gene ID: 4792
• mRNA Refseq: NM_020529
• Protein Refseq: NP_065390
• MIM: 164008
• UniProt ID: P25963