Recombinant Human NFKBIA Protein, MYC/DDK-tagged

• Cat.No.: NFKBIA-819H
• Product Overview: Recombinant human NFKBIA protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Description: This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
• Source: HEK293
• Species: Human
• Tag: MYC/DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 35.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: NFKB inhibitor alpha[ Homo sapiens ]
• Official Symbol: NFKBIA
• Synonyms: IKBA; MAD-3; NFKBI
• Gene ID: 4792
• mRNA Refseq: NM_020529.2
• Protein Refseq: NP_065390
• MIM: 164008
• UniProt ID: P25963