Recombinant Human NFYA Protein
Cat.No. : | NFYA-202H |
Product Overview : | Recombinant Human NFYA, transcript variant 2, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds to CCAAT motifs in the promoter regions in a variety of genes. Subunit A associates with a tight dimer composed of the B and C subunits, resulting in a trimer that binds to DNA with high specificity and affinity. The sequence specific interactions of the complex are made by the A subunit, suggesting a role as the regulatory subunit. In addition, there is evidence of post-transcriptional regulation in this gene product, either by protein degradation or control of translation. Further regulation is represented by alternative splicing in the glutamine-rich activation domain, with clear tissue-specific preferences for the two isoforms. |
Source : | E. coli |
Species : | Human |
Form : | Lyophilized from a 0.2 µM filtered solution of PBS, pH 7.4 |
Molecular Mass : | 33.9kD |
AA Sequence : | MEQYTANSNSSTEQIVVQAGQIQQQ VQGQPLMVQVSGGQLITSTGQPIMV QAVPGGQGQTIMQVPVSGTQGLQQI QLVPPGQIQIQGGQAVQVQGQQGQT QQIIIQQPQTAVTAGQTQTQQQIAV QGQQVAQTAEGQTIVYQPVNADGTI LQQVTVPVSGMITIPAASLAGAQIV QTGANTNTTSSGQGTVTVTLPVAGN VVNSGGMVMMVPGAGSVPAIQRIPL PGAEMLEEEPLYVNAKQYNRILKRR QARAK |
Endotoxin : | Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
Purity : | >95% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
Gene Name : | NFYA nuclear transcription factor Y, alpha [ Homo sapiens ] |
Official Symbol : | NFYA |
Synonyms : | NFYA; nuclear transcription factor Y, alpha; nuclear transcription factor Y subunit alpha; CBF B; HAP2; NF YA; HAP2 CCAAT-binding protein; Transcription factor NF-Y, A subunit; CAAT box DNA-binding protein subunit A; CAAT-box DNA binding protein subunit A; nuclear transcription factor Y subunit A; CCAAT-binding transcription factor subunit B; CBF-A; CBF-B; NF-YA; FLJ11236; |
Gene ID : | 4800 |
mRNA Refseq : | M_021705 |
Protein Refseq : | NP_068351 |
MIM : | 189903 |
UniProt ID : | P23511 |
Products Types
◆ Recombinant Protein | ||
NFYA-3636R | Recombinant Rat NFYA Protein, His (Fc)-Avi-tagged | +Inquiry |
NFYA-2838R | Recombinant Rhesus Macaque NFYA Protein, His (Fc)-Avi-tagged | +Inquiry |
NFYA-3619H | Recombinant Human NFYA Protein, His (Fc)-Avi-tagged | +Inquiry |
NFYA-5207Z | Recombinant Zebrafish NFYA | +Inquiry |
NFYA-4698H | Recombinant Human NFYA Protein (Met1-Ser318), N-Gst tagged | +Inquiry |
◆ Lysates | ||
NFYA-3840HCL | Recombinant Human NFYA 293 Cell Lysate | +Inquiry |
NFYA-3841HCL | Recombinant Human NFYA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All NFYA Products
Required fields are marked with *
My Review for All NFYA Products
Required fields are marked with *
0
Inquiry Basket