| Description : |
This gene encodes a member of the type-B carboxylesterase/lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and Asperger syndrome. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
91.7 kDa |
| AA Sequence : |
MSRPQGLLWLPLLFTPVCVMLNSNV LLWLTALAIKFTLIDSQAQYPVVNT NYGKIRGLRTPLPNEILGPVEQYLG VPYASPPTGERRFQPPEPPSSWTGI RNTTQFAAVCPQHLDERSLLHDMLP IWFTANLDTLMTYVQDQNEDCLYLN IYVPTEDDIHDQNSKKPVMVYIHGG SYMEGTGNMIDGSILASYGNVIVIT INYRLGILGFLSTGDQAAKGNYGLL DQIQALRWIEENVGAFGGDPKRVTI FGSGAGASCVSLLTLSHYSEGLFQK AIIQSGTALSSWAVNYQPAKYTRIL ADKVGCNMLDTTDMVECLRNKNYKE LIQQTITPATYHIAFGPVIDGDVIP DDPQILMEQGEFLNYDIMLGVNQGE GLKFVDGIVDNEDGVTPNDFDFSVS NFVDNLYGYPEGKDTLRETIKFMYT DWADKENPETRRKTLVALFTDHQWV APAVATADLHAQYGSPTYFYAFYHH CQSEMKPSWADSAHGDEVPYVFGIP MIGPTELFSCNFSKNDVMLSAVVMT YWTNFAKTGDPNQPVPQDTKFIHTK PNRFEEVAWSKYNPKDQLYLHIGLK PRVRDHYRATKVAFWLELVPHLHNL NEIFQYVSTTTKVPPPDMTSFPYGT RRSPAKIWPTTKRPAITPANNPKHS KDPHKTGPEDTTVLIETKRDYSTEL SVTIAVGASLLFLNILAFAALYYKK DKRRHETHRRPSPQRNTTNDIAHIQ NEEIMSLQMKQLEHDHECESLQAHD TLRLTCPPDYTLTLRRSPDDIPLMT PNTITMIPNTLTGMQPLHTFNTFSG GQNSTNLPHGHSTTRVTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
