Recombinant Human NLRP10 Protein, Myc/DDK-tagged, C13 and N15-labeled
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Cat.No. : | NLRP10-5638H |
Product Overview : | NLRP10 MS Standard C13 and N15-labeled recombinant protein (NP_789791) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
Description : | Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 75 kDa |
AA Sequence : | MAMAKARKPR EALLWALSDL EENDFKKLKF YLRDMTLSEG QPPLARGELE GLIPVDLAEL LISKYGEKEA VKVVLKGLKV MNLLELVDQL SHICLHDYRE VYREHVRCLE EWQEAGVNGR YNQVLLVAKP SSESPESLAC PFPEQELESV TVEALFDSGE KPSLAPSLVV LQGSAGTGKT TLARKMVLDW ATGTLYPGRF DYVFYVSCKE VVLLLESKLE QLLFWCCGDN QAPVTEILRQ PERLLFILDG FDELQRPFEE KLKKRGLSPK ESLLHLLIRR HTLPTCSLLI TTRPLALRNL EPLLKQARHV HILGFSEEER ARYFSSYFTD EKQADRAFDI VQKNDILYKA CQVPGICWVV CSWLQGQMER GKVVLETPRN STDIFMAYVS TFLPPDDDGG CSELSRHRVL RSLCSLAAEG IQHQRFLFEE AELRKHNLDG PRLAAFLSSN DYQLGLAIKK FYSFRHISFQ DFFHAMSYLV KEDQSRLGKE SRREVQRLLE VKEQEGNDEM TLTMQFLLDI SKKDSFSNLE LKFCFRISPC LAQDLKHFKE QMESMKHNRT WDLEFSLYEA KIKNLVKGIQ MNNVSFKIKH SNEKKSQSQN LFSVKSSLSH GPKEEQKCPS VHGQKEGKDN IAGTQKEAST GKGRGTEETP KNTYITRTRP LEQKLISEED LAANDILDYK DDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
SDS-PAGE : |
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Gene Name : | NLRP10 NLR family pyrin domain containing 10 [ Homo sapiens (human) ] |
Official Symbol : | NLRP10 |
Synonyms : | NLRP10; NLR family, pyrin domain containing 10; NACHT, leucine rich repeat and PYD containing 10, NALP10; NACHT, LRR and PYD domains-containing protein 10; CLR11.1; NOD8; nucleotide binding oligomerization domain; leucine rich repeat and pyrin domain containing 10; PAN5; Pynod; NACHT, leucine rich repeat and PYD containing 10; nucleotide-binding oligomerization domain protein 8; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10; PYNOD; NALP10; |
Gene ID : | 338322 |
mRNA Refseq : | NM_176821 |
Protein Refseq : | NP_789791 |
MIM : | 609662 |
UniProt ID : | Q86W26 |
◆ Recombinant Protein
Nlrp10-4434M | Recombinant Mouse Nlrp10 Protein, Myc/DDK-tagged | +Inquiry |
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◆ Lysates
NLRP10-3803HCL | Recombinant Human NLRP10 293 Cell Lysate | +Inquiry |
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NLRP12NLRP3NLRP1NLRP2NLRP4NLRP10NLRP11NLRP6NLRP13NLRP14NLRP7NLRP8NLRP9NLRP5Nlrp1aNlrp1bNlrp4aNlrp4bNlrp4cNlrp4eNlrp4fNlrp4gNlrp9aNlrp9bNlrp9c
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