Recombinant Human NLRP3 protein, GST-tagged

• Cat.No.: NLRP3-186H
• Product Overview: Recombinant Human PNLRP3(1 a.a. - 1036 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 144.6 kDa
• AA Sequence: MKMASTRCKLARYLEDLEDVDLKKF KMHLEDYPPQKGCIPLPRGQTEKAD HVDLATLMIDFNGEEKAWAMAVWIF AAINRRDLYEKAKRDEPKWGSDNAR VSNPTVICQEDSIEEEWMGLLEYLS RISICKMKKDYRKKYRKYVRSRFQC IEDRNARLGESVSLNKRYTRLRLIK EHRSQQEREQELLAIGKTKTCESPV SPIKMELLFDPDDEHSEPVHTVVFQ GAAGIGKTILARKMMLDWASGTLYQ DRFDYLFYIHCREVSLVTQRSLGDL IMSCCPDPNPPIHKIVRKPSRILFL MDGFDELQGAFDEHIGPLCTDWQKA ERGDILLSSLIRKKLLPEASLLITT RPVALEKLQHLLDHPRHVEILGFSE AKRKEYFFKYFSDEAQARAAFSLIQ ENEVLFTMCFIPLVCWIVCTGLKQQ MESGKSLAQTSKTTTAVYVFFLSSL LQPRGGSQEHGLCAHLWGLCSLAAD GIWNQKILFEESDLRNHGLQKADVS AFLRMNLFQKEVDCEKFYSFIHMTF QEFFAAMYYLLEEEKEGRTNVPGSR LKLPSRDVTVLLENYGKFEKGYLIF VVRFLFGLVNQERTSYLEKKLSCKI SQQIRLELLKWIEVKAKAKKLQIQP SQLELFYCLYEMQEEDFVQRAMDYF PKIEINLSTRMDHMVSSFCIENCHR VESLSLGFLHNMPKEEEEEEKEGRH LDMVQCVLPSSSHAACSHGLVNSHL TSSFCRGLFSVLSTSQSLTELDLSD NSLGDPGMRVLCETLQHPGCNIRRL WLGRCGLSHECCFDISLVLSSNQKL VELDLSDNALGDFGIRLLCVGLKHL LCNLKKLWLVSCCLTSACCQDLASV LSTSHSLTRLYVGENALGDSGVAIL CEKAKNPQCNLQKLGLVNSGLTSVC CSALSSVLSTNQNLTHLYLRGNTLG DKGIKLLCEGLLHPDCKLQVLELDN CNLTSHCCWDLSTLLTSSQSLRKLS LGNNDLGDLGVMMFCEVLKQQSCLL QNLGLSEMYFNYETKSALETLQEEK PELTVVFEPSW
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: NLRP3 NLR family, pyrin domain containing 3 [ Homo sapiens ]
• Official Symbol: NLRP3
• Synonyms: NLRP3; NLR family, pyrin domain containing 3; C1orf7, CIAS1, cold autoinflammatory syndrome 1; NACHT, LRR and PYD domains-containing protein 3; AGTAVPRL; AII; AVP; CLR1.1; Cryopyrin; FCAS; FCU; MWS; NALP3; nucleotide binding oligomerization domain; leucine rich repeat and pyrin domain containing 3; PYPAF1; cryopyrin; caterpiller protein 1.1; PYRIN-containing APAF1-like protein 1; NACHT, LRR and PYD containing protein 3; cold autoinflammatory syndrome 1 protein; NACHT domain-, leucine-rich repeat-, and PYD-containing protein 3; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 3; CIAS1; C1orf7; FLJ95925
• Gene ID: 114548
• mRNA Refseq: NM_004895
• Protein Refseq: NP_004886
• MIM: 606416
• UniProt ID: Q96P20
• Chromosome Location: 1q44
• Pathway: Immune System, organism-specific biosystem; Inflammasomes, organism-specific biosystem; Influenza A, organism-specific biosystem; Influenza A, conserved biosystem; Innate Immune System, organism-specific biosystem; NOD-like receptor signaling pathway, organism-specific biosystem; NOD-like receptor signaling pathway, conserved biosystem
• Function: ATP binding; nucleotide binding; peptidoglycan binding; protein binding