Recombinant Human NME3 protein, His-tagged NME3-202H

Recombinant Human NME3 protein, His-tagged

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Recombinant Human NME3 protein, His-tagged

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Cat.No. : NME3-202H
Product Overview : Recombinant human NME3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description : NME3, also known as, a potential suppressor of metastasis, is expressed at a much lower level in highly metastatic cells than in cells with lower metastatic potential. It is important for the synthesis of nucleoside triphosphates and may play a role in apoptosis induction and hematopoiesis. It is preferentially expressed during early stages of myeloid differentiation of highly purified CD34+ cells.
Source : E.coli
Species : Human
Tag : His
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 50% glycerol, 0.1M NaCl, 2mM DTT
Bio-activity : Specific activity is > 150 units/mg, and is defined as the amount of enzyme that convert 1.0 umole each of ATP and TDP to ADP and TTP per minute at pH 7.5 at 25C in a couple system with PK/LDH.
Molecular Mass : 19.1 kDa (169aa), confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MERTFLAVKP DGVQRRLVGE IVRRFERKGF KLVALKLVQA SEELLREHYA ELRERPFYGR LVKYMASGPVVAMVWQGLDV VRTSRALIGA TNPADAPPGT IRGDFCIEVG KNLIHGSDSV ESARREIALW FRADELLCWE DSAGHWLYE
Purity : > 95% by SDS - PAGE
Storage : Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : NME3 non-metastatic cells 3, protein expressed in [ Homo sapiens ]
Official Symbol : NME3
Synonyms : NME3; non-metastatic cells 3, protein expressed in; nucleoside diphosphate kinase 3; DR nm23; NM23 H3; NDK 3; NDP kinase 3; NDP kinase C; nucleoside diphosphate kinase C; NDPKC; NDPK-C; NM23H3; DR-nm23; NM23-H3; c371H6.2; KIAA0516;
Gene ID : 4832
mRNA Refseq : NM_002513
Protein Refseq : NP_002504
MIM : 601817
UniProt ID : Q13232
Chromosome Location : 16q13.3
Pathway : Metabolic pathways, organism-specific biosystem; Purine metabolism, organism-specific biosystem; Purine metabolism, conserved biosystem; Pyrimidine metabolism, organism-specific biosystem; Pyrimidine metabolism, conserved biosystem; Pyrimidine ribonucleotide biosynthesis, UMP => UDP/UTP,CDP/CTP, organism-specific biosystem;
Function : ATP binding; kinase activity; metal ion binding; nucleoside diphosphate kinase activity; nucleotide binding; transferase activity;

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