| Description : |
This gene encodes a protein originally thought to be related to the collagenase gene family. This gene is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development. Mutations in ABCC6, which is located nearby, rather than mutations in this gene are associated with pseudoxanthoma elasticum (PXE). Two transcripts encoding different isoforms have been described. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
134 kDa |
| AA Sequence : |
MLVGQGAGLLGPAVVTAAVVLLLSG VGPAHGSEDIVVGCGGFVKSDVEIN YSLIEIKLYTKHGTLKYQTDCAPNN GYFMIPLYDKGDFILKIEPPLGWSF EPTTVELHVDGVSDICTKGGDINFV FTGFSVNGKVLSKGQPLGPAGVQVS LRNTGTEAKIQSTVTQPGGKFAFFK VLPGDYEILATHPTWALKEASTTVR VTNSNANAASPLIVAGYNVSGSVRS DGEPMKGVKFLLFSSLVTKEDVLGC NVSPVPGFQPQDESLVYLCYTVSRE DGSFSFYSLPSGGYTVIPFYRGERI TFDVAPSRLDFTVEHDSLKIEPVFH VMGFSVTGRVLNGPEGDGVPEAVVT LNNQIKVKTKADGSFRLENITTGTY TIHAQKEHLYFETVTIKIAPNTPQL ADIVATGFSVCGRISIIRFPDTVKQ MNKYKVVLSSQDKDKSLVTVETDAH GSFCFKAKPGTYKVQVMVPEAETRA GLTLKPQTFPLTVTDRPVMDVAFVQ FLASVSGKVSCLDTCGDLLVTLQSL SRQGEKRSLQLSGKVNAMTFTFDNV LPGKYKISIMHEDWCWKNKSLEVEV LEDDVSAVEFRQTGYMLRCSLSHAI TLEFYQDGNGRENVGIYNLSKGVNR FCLSKPGVYKVTPRSCHRFEQAFYT YDTSSPSILTLTAIRHHVLGTITTD KMMDVTVTIKSSIDSEPALVLGPLK SVQELRREQQLAEIEARRQEREKNG NEEGEERMTKPPVQEMVDELQGPFS YDFSYWARSGEKITVTPSSKELLFY PPSMEAVVSGESCPGKLIEIHGKAG LFLEGQIHPELEGVEIVISEKGASS PLITVFTDDKGAYSVGPLHSDLEYT VTSQKEGYVLTAVEGTIGDFKAYAL AGVSFEIKAEDDQPLPGVLLSLSGG LFRSNLLTQDNGILTFSNLSPGQYY FKPMMKEFRFEPSSQMIEVQEGQNL KITITGYRTAYSCYGTVSSLNGEPE QGVAMEAVGQNDCSIYGEDTVTDEE GKFRLRGLLPGCVYHVQLKAEGNDH IERALPHHRVIEVGNNDIDDVNIIV FRQINQFDLSGNVITSSEYLPTLWV KLYKSENLDNPIQTVSLGQSLFFHF PPLLRDGENYVVLLDSTLPRSQYDY ILPQVSFTAVGYHKHITLIFNPTRK LPEQDIAQGSYIALPLTLLVLLAGY NHDKLIPLLLQLTSRLQGVGALGQA ASDNSGPEDAKRQAKKQKTRRTTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
