Recombinant Human NPR2 Protein (23-458 aa), His-SUMO-tagged

• Cat.No.: NPR2-691H
• Product Overview: Recombinant Human NPR2 Protein (23-458 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Cardiovascular. Protein Description: Partial.

Specification

• Description: Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.
• Source: E. coli
• Species: Human
• Tag: His-SUMO
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 64.5 kDa
• Protein length: 23-458 aa
• AA Sequence: RNLTLAVVLPEHNLSYAWAWPRVGP AVALAVEALGRALPVDLRFVSSELE GACSEYLAPLSAVDLKLYHDPDLLL GPGCVYPAASVARFASHWRLPLLTA GAVASGFSAKNDHYRTLVRTGPSAP KLGEFVVTLHGHFNWTARAALLYLD ARTDDRPHYFTIEGVFEALQGSNLS VQHQVYAREPGGPEQATHFIRANGR IVYICGPLEMLHEILLQAQRENLTN GDYVFFYLDVFGESLRAGPTRATGR PWQDNRTREQAQALREAFQTVLVIT YREPPNPEYQEFQNRLLIRAREDFG VELGPSLMNLIAGCFYDGILLYAEV LNETIQEGGTREDGLRIVEKMQGRR YHGVTGLVVMDKNNDRETDFVLWAM GDLDSGDFQPAAHYSGAEKQIWWTG RPIPWVKGAPPSDNPPCAFDLDDPS CDKTPLSTLAI
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: NPR2 natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B) [ Homo sapiens ]
• Official Symbol: NPR2
• Synonyms: NPR2; ANPb; GUCY2B; GC-B; ANP-B; NPR-B; ANPR-B; AMDM; NPRB; ANPRB; GUC2B; NPRBi
• Gene ID: 4882
• mRNA Refseq: NM_003995
• Protein Refseq: NP_003986
• MIM: 108961
• UniProt ID: P20594