Recombinant Human NPTX2 Protein, MYC/DDK-tagged

• Cat.No.: NPTX2-1268H
• Product Overview: Recombinant human NPTX2 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD. [provided by RefSeq, Feb 2009]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 46.9 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: NPTX2 neuronal pentraxin II [ Homo sapiens ]
• Official Symbol: NPTX2
• Synonyms: NARP; NP-II; NP2
• Gene ID: 4885
• mRNA Refseq: NM_002523
• Protein Refseq: NP_002514
• MIM: 600750
• UniProt ID: P47972