Recombinant Human NRG3 Protein (1-360 aa), His-SUMO-tagged

• Cat.No.: NRG3-1791H
• Product Overview: Recombinant Human NRG3 Protein (1-360 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Cancer. Protein Description: Partial.

Specification

• Description: Direct ligand for the ERBB4 tyrosine kinase receptor. Binding results in ligand-stimulated tyrosine phosphorylation and activation of the receptor. Does not bind to the EGF receptor, ERBB2 or ERBB3 receptors. May be a survival factor for oligodendrocytes.
• Source: E. coli
• Species: Human
• Tag: His-SUMO
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 53.8 kDa
• Protein length: 1-360 aa
• AA Sequence: MSEGAAAASPPGAASAAAASAEEGT AAAAAAAAAGGGPDGGGEGAAEPPR ELRCSDCIVWNRQQTWLCVVPLFIG FIGLGLSLMLLKWIVVGSVKEYVPT DLVDSKGMGQDPFFLSKPSSFPKAM ETTTTTTSTTSPATPSAGGAASSRT PNRISTRLTTITRAPTRFPGHRVPI RASPRSTTARNTAAPATVPSTTAPF FSSSTLGSRPPVPGTPSTQAMPSWP TAAYATSSYLHDSTPSWTLSPFQDA ASSSSSSSSSATTTTPETSTSPKFH TTTYSTERSEHFKPCRDKDLAYCLN DGECFVIETLTGSHKHCRCKEGYQG VRCDQFLPKTDSILSDPTDHLGIEF MESEEVYQRQ
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: NRG3 neuregulin 3 [ Homo sapiens ]
• Official Symbol: NRG3
• Synonyms: NRG3; neuregulin 3; neuregulin 3 variant 1; neuregulin 3 variant 3; HRG3; pro-NRG3
• Gene ID: 10718
• mRNA Refseq: NM_001010848
• Protein Refseq: NP_001010848
• MIM: 605533
• UniProt ID: P56975