Recombinant Human NRG3 Protein, Fc-tagged

• Cat.No.: NRG3-762H
• Product Overview: Recombinant human NRG3 (NP_001159444.1) (Glu282-Pro342) was expressed with the Fc region of human IgG1 at the C-terminus.

Specification

• Species: Human
• Source: HEK293
• Tag: Fc
• Protein Length: 282-342 a.a.
• Predicted N Terminal: Glu
• Form: Lyophilized from sterile PBS, pH 7.4, 5% ~ 8% trehalose and mannitol.
• Molecular Mass: The recombinant human NRG3 consists 299 amino acids and predicts a molecular mass of 33.7 kDa.
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE.
• Stability: Samples are stable for up to twelve months from date of receipt at -70ºC.
• Storage: Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: NRG3 neuregulin 3 [ Homo sapiens ]
• Official Symbol: NRG3
• Synonyms: NRG3; neuregulin 3; pro-neuregulin-3, membrane-bound isoform; neuregulin 3 variant 1; neuregulin 3 variant 3; neuregulin 3 variant 4; neuregulin 3 variant 5; neuregulin 3 variant 6; neuregulin 3 variant 7; neuregulin 3 variant 8; neuregulin 3 variant 9; neuregulin 3 variant 10; neuregulin 3 variant 11; neuregulin 3 variant 12; neuregulin 3 variant 13; neuregulin 3 variant 14; neuregulin-3-like polypeptide; HRG3; pro-NRG3
• Gene ID: 10718
• mRNA Refseq: NM_001010848
• Protein Refseq: NP_001010848
• MIM: 605533
• UniProt ID: P56975
• Chromosome Location: 10q22-q23
• Pathway: ErbB receptor signaling network, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, organism-specific biosystem; ErbB signaling pathway, conserved biosystem; ErbB4 signaling events, organism-specific biosystem; GRB2 events in ERBB2 signaling, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem