Recombinant Human NSD2 Protein, GST-tagged

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Recombinant Human NSD2 Protein, GST-tagged

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Cat.No. : NSD2-022H
Product Overview : Recombinant Human NSD2 protein (941-1240) with a N-terminal GST-tag was expressed in E. coli.
Description : This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : 61.2 kDa
Protein length : 941-1240
Purity : ≥80% estimated by SDS-PAGE
Stability : ≥ 1 year
Storage : -80 centigrade
SDS-PAGE Analysis of NSD2. :

Lane 1: MW Standards
Lane 2: NSD2 (1 μg)
Lane 3: NSD2 (5 μg)

Gene Name : NSD2 nuclear receptor binding SET domain protein 2 [ Homo sapiens (human) ]
Official Symbol : NSD2
Synonyms : NSD2; nuclear receptor binding SET domain protein 2; WHS; TRX5; KMT3F; KMT3G; MMSET; WHSC1; REIIBP; histone-lysine N-methyltransferase NSD2; IL5 promoter REII region-binding protein; Wolf-Hirschhorn syndrome candidate 1; multiple myeloma SET domain containing protein type III; nuclear SET domain-containing protein 2; probable histone-lysine N-methyltransferase NSD2; trithorax/ash1-related protein 5; EC 2.1.1.356
Gene ID : 7468
mRNA Refseq : NM_001042424
Protein Refseq : NP_001035889
MIM : 602952
UniProt ID : O96028

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